Research

The Saban Research Institute

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Interested in a clinical trial? Search by condition, phase or study type and see what The Saban Research Institute has to offer.

Core Facilities

Children’s Hospital Los Angeles supports several shared research facilities, known as cores, which house specialized scientific equipment and offer expert services.

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Biostatistics and Data Management Core

Cellular Imaging Core

CHLA Core Pilot Program

Data Science & AI Team

Extracellular Vesicle Core

Flow Cytometry Core

Good Manufacturing Practice Core

Human Imaging Core

Molecular Pathology Genomics Core

Neuropsychology Core

Nutrition and Metabolic Core

Small Animal Imaging Core

Spatial Biology and Genomics Core

Stem Cell Core

Laboratories

The Saban Research Building and Smith Research Tower provide more than 150,000 square feet of state-of-the-art bench laboratory space and facilities dedicated to leading-edge research.

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Amatruda Lab

The Amatruda Lab’s primary research and clinical focus is on solid tumors that develop during childhood, including sarcomas, germ cell tumors and Wilms tumor.

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GOFARR Laboratory for Organ Regenerative Research and Cell Therapeutics in Urology

The GOFARR Laboratory focuses on the development of new stem cell therapeutics and other techniques for organ regeneration.

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The Schumacher Gut Science Lab studies immune and epithelial drivers of tissue remodeling, function and regeneration in the gut with a focus on discovering new ways to treat intestinal inflammatory diseases like ulcerative colitis and Crohn's disease.

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Meet Our Researchers

The physicians and scientists at The Saban Research Institute are uncovering answers that will bring hope and healthier futures to children’s health care.

Meet our researchers

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Research Blog

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Research and Breakthroughs

Team Uses Low-Field MRI to Improve Lung Care for Children

February 3, 2025

New research at CHLA is harnessing low-field MRI to improve the diagnosis—and treatment—of lung disease in children.

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Research and Breakthroughs

Q&A: What’s Next for Hemophilia Gene Therapy?

January 27, 2025

An international expert at CHLA talks about the state of hemophilia gene therapy—and what’s on the horizon.

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Research and Breakthroughs

‘Gated’ CAR T-Cells Are Effective Against AML—With Less Toxicity

January 21, 2025

The novel approach marks a significant step forward in developing CAR T-cell therapy for acute myeloid leukemia.

Investing in Our People

Developing the careers of new and established physicians and scientists is a key driver of scientific advancement. Find out how we support our team, and learn how to become part of it.