Content related to Children’s Hospital Los Angeles Team Identifies Developmental Stage for No. 1 Eye Tumor in Children

Researchers are working to uncover a cause for retinoblastoma, the most common eye cancer in children. They have published promising results in the journal Nature.

Microscopic image: MDM2 expression (in red) in retinoblastoma Rb176 cells. Credit: Donglai Qi, PhD, and David Cobrinik, MD, PhD. Researchers at The Saban Research Institute of Children’s Hospital Los

Retinoblastoma is a common eye cancer in children. David Cobrinik of The Vision Center has helped answer the question of why mutations to the RB1 gene primarily cause tumors of the retina.

Cultured retinoblastoma tumor containing tumor cells (red) and fibroblasts (green). Researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) have demonstrated that

A new study finds a reason, paving the way for the development of new, more effective treatments.