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When Good Immune Cells Turn Bad

October 10, 2017

Investigators at the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles have identified new findings about an immune cell – called a tumor-associated macrophage – that

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When Good Macrophages go Bad

December 5, 2018

New study reveals how cancer manipulates our immune system to become harder to treat Many factors affect cancer treatment outcome, such as the size and location of the tumor, availability of effective

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Treating Neuroblastoma: With or Without G-CSF?

May 19, 2015

A recent study found that the growth factor G-CSF, used in high-risk neuroblastoma treatment, leads to increased tumor growth and metastasis. Investigators think the benefits still outweigh the risks.

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Treatment Significantly Reduces Chemotherapy-Induced Hearing Loss in Children

December 6, 2016

Investigators from Children’s Hospital Los Angeles and 37 other Children’s Oncology Group hospitals in the U.S. and Canada have determined that sodium thiosulfate prevents cisplatin-induced hearing

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Rare Insight: A New Approach Optimizes Hepatoblastoma Cancer Treatment

February 14, 2022

A Children’s Hospital Los Angeles study validates a new risk assessment for hepatoblastoma and finds some histological characteristics also predict prognosis.

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Combination Therapy May Offer Better Outcomes for Patients with Retinoblastoma

April 19, 2016

Cultured retinoblastoma tumor containing tumor cells (red) and fibroblasts (green). Researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) have demonstrated that

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St. Baldrick’s Foundation Supports Innovative Research in Pediatric Cancer at CHLA

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Research and Breakthroughs

Oncoproteins Interact to Promote Cancer Cell Growth in Retinoblastoma

October 17, 2016

Microscopic image: MDM2 expression (in red) in retinoblastoma Rb176 cells. Credit: Donglai Qi, PhD, and David Cobrinik, MD, PhD. Researchers at The Saban Research Institute of Children’s Hospital Los

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Why do some neuroblastoma patients have “dancing eyes”?

August 5, 2015

Opsoclonus-Myoclonus Syndrome or OMS (also known as the “dancing eyes” syndrome) affects roughly 1 in every 200 patients with neuroblastoma, a cancer of the sympathetic nervous system.

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