David Warburton, OBE, OFM, KGE, KJ, DSc, MD, MMM, FRCP, FRCS, FRCPCH, FAAAS, FAPS, ATSF, FAAP

Vice Chair, Surgical Research, Department of Surgery

Pasadena Guild Chair in Developmental Biology and Regenerative Medicine

Professor of Pediatrics, Surgery and Craniofacial Molecular Biology, USC Keck School of Medicine and Ostrow School of Dentistry

Professor The Chevalier David Warburton is tenured and endowed as the Pasadena Guild Professor of Pediatrics and Neonatal-Perinatal Medicine in the Division of Neonatology, Fetal and Neonatal Institute at the Children’s Hospital Los Angeles and the Keck School of Medicine and the University of Southern California.

Dr. Warburton is a Fellow of the Royal Colleges of Paediatrics and Child Health, Physicians, Surgeons and Tropical Medicine and Hygiene as well as a Fellow of the American Thoracic Society, the American Physiological Society and the American Association of the Advancement of Science. He is a member of the American Pediatric Society and of the Society for Pediatric Research.

He has been decorated by the Queen of England as an Officer of the Most Excellent Order of the British Empire, as a Hero of The Order of Friendship of Mongolia, he is a Knight Commander of the Order of St George and a Knight of the Order of St Joachim, all awarded for his medical research and global humanitarian work.

Dr. Warburton was educated at Enfield Grammar School and St Thomas’s Hospital Medical School (now affiliated with King’s College) in London, UK, receiving degrees in Physiology, Medicine and Surgery as well as a Higher Doctorate of Science from the University of London and a degree in medical management from the University of Southern California. He took postgraduate training in London, at Harvard and Brown. He joined the Neonatal-Respiratory Diseases Division at Children’s Hospital Los Angeles in 1979. He is Board certified in Pediatrics and Neonatal-Perinatal Medicine.

Dr. Warburton holds the Pasadena Guild David Warburton Chair in Human Developmental Biology research. He presently serves as the Hub PI for the NIH RECOVER COVID Program as well as Chair of the Publications committee, serves on the Pediatrics steering committee and the National Systems Biology committee as well as swerving on the IPC4 international committee.

Education

Medical School

St Thomas’s Hospital Medical School, University of London, UK

Graduate School

DSc, King's College, University of London
MMM, Marshall School of Business, University of Southern California
St Thomas’s Hospital Medical School, University of London, UK

Internship

Medicine (Cardiology) and General Surgery, St Thomas's Hospital, University of London

Residency

Pediatrics, St Thomas's Hospital, University of London
Pediatric Cardiology, Royal Brompton Hospital
Pediatrics, Harvard University, Children's Hospital Medical Center, Boston

Fellowship

Neonatal-Perinatal Medicine, Women and Infants Hospital of Rhode Island
Clinical Pediatric Fellow, Boston Children’s Hospital, Harvard, Boston, MA
MMM Marshall School of Business, University of Southern California

Accomplishments

Certifications

Board Certified in Pediatrics and Sub Board Certified in Neonatal-Perinatal Medicine

Professional Memberships

Royal College of Physicians of Edinburgh
Royal College of Surgeons of England
Royal College of Pediatrics and Child Health
American Thoracic Society
American Pediatric Society
Society for Pediatric Research
American Association for the Advancement of Science
American Academy of Pediatrics
American Physiological Society
Royal College of Tropical Medicine and Hygiene

Awards

Beanie Prize in Obstetrics and Gynaecology
Bhatia Medal and Prize in Paediatrics
Officer of the Most Excellent Order of the British Empire
Order of the Silver Falcon of Mongolia
Presidential Medal of the Mongolian National University of the Medical Sciences
Hero of the Order of Friendship of Mongolia
Knight Commander of the Order of the Eagle of Georgia
Knight of the Order of St Joachim
Freedom of the City of Ulaanbaatar, Mongolia
Yvette Mayant-Rothschild Professeur de L’Institut Curie, Paris
Rappaport Professor, Technion, Israel
Rothschild Professor, Hadassah, Israel
Fogarty Professor, University of Dundee, Scotland (twice)
Honored Professor of Public Health, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
Professor of Pediatrics, National Center for Maternal and Child Health, Ulaanbaatar, Mongolia
Over 200 invited lectureships and visiting Professorships

Funding

UO1HL12268 Warburton (P.I.) $4,000,000 06/14/2014-04/30/19
NHLBI
Molecular anatomy of human alveolar development
This UO1 grant is to make a detailed molecular map of human and mouse alveolarization.

1D43ES02286201 Warburton (P.I.) $2,000,000 02/14/13-01/31/18
NIH NIEHS
Environmental and Respiratory Health Across the Lifespan in Mongolia
This DE43 grant is to do field capacity building and research on the effects of air pollution on lung health.

W81XWH-16-1-0253 Warburton (P.I.) $2,000,000 09/01/16-08/31/19
PR150666 / U.S. Army Medical Research Acquisition Activity
Lung injury; relates to real time endoscopic monitoring of single cells’ respiratory health in lung
In this proposal we will set up and tune a new technology that quantifies the intrinsic cellular metabolism of lung cells, which can thus be applied as a portable diagnostic tool for lung injury.

Philanthropic support: Pasadena Guild Endowments, Children’s Hospital Los Angeles, Webb Foundation, Garland Foundation

Areas of Focus

Pediatrics
Neonatal-Perinatal Medicine
Personalized integration of specialized care
Medico-legal consulting

USC Bio Link

USC Biography

Publications

Ardini-Poleske ME, Clark RF, Ansong C, Carson JP, Corley RA, Deutsch GH, Hagood JS, Kaminski N, Mariani TJ, Potter SS, Pryhuber GS, Warburton D, Whitsett JA, Palmer SM, Ambalavanan N; LungMAP Consortium. LungMAP: The Molecular Atlas of Lung Development Program. Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L733-L740. doi: 10.1152/ajplung.00139.2017. Epub 2017 Aug 10. PMID: 28798251; PMCID: PMC5792185.

Warburton D. Overview of Lung Development in the Newborn Human. Neonatology. 2017;111(4):398-401. doi: 10.1159/000458465. Epub 2017 May 25. PMID: 28538234; PMCID: PMC5538827.

Navarro S, Reddy R, Lee J, Warburton D, Driscoll B. Inhaled resveratrol treatments slow ageing-related degenerative changes in mouse lung. Thorax. 2017 May;72(5):451-459. doi: 10.1136/thoraxjnl-2016-208964. Epub 2017 Jan 9. PMID: 28070015.

Warburton D, Gilliland F, Dashdendev B. Environmental pollution in Mongolia: effects across the lifespan. Environ Res. 2013 Jul;124:65-6. doi: 10.1016/j.envres.2013.04.002. Epub 2013 May 11. PMID: 23673312; PMCID: PMC4043223.

Warburton D. Developmental biology: order in the lung. Nature. 2008 Jun 5;453(7196):733-5. doi: 10.1038/453733a. PMID: 18528385; PMCID: PMC2865228.

Rao S, Gross RS, Mohandas S, Stein CR, Case A, Dreyer B, Pajor NM, Bunnell HT, Warburton D, Berg E, Overdevest JB, Gorelik M, Milner J, Saxena S, Jhaveri R, Wood JC, Rhee KE, Letts R, Maughan C, Guthe N, Castro-Baucom L, Stockwell MS. Postacute Sequelae of SARS-CoV-2 in Children. Pediatrics. 2024 Mar 1;153(3):e2023062570. doi: 10.1542/peds.2023-062570. PMID: 38321938; PMCID: PMC10904902.

Gross RS, Thaweethai T, Kleinman LC, Snowden JN, Rosenzweig EB, Milner JD, Tantisira KG, Rhee KE, Jernigan TL, Kinser PA, Salisbury AL, Warburton D, et al. Characterizing Long COVID in Children and Adolescents. JAMA. 2024 Aug 21;332(14):1174–88. doi: 10.1001/jama.2024.12747. Epub ahead of print. PMID: 39196964; PMCID: PMC11339705.

Griese M, Kurland G, Cidon M, Deterding RR, Epaud R, Nathan N, Schwerk N, Warburton D, Weinman JP, Young LR, Deutsch GH. Pulmonary fibrosis may begin in infancy: from childhood to adult interstitial lung disease. Thorax. 2024 Nov 14;79(12):1162-1172. doi: 10.1136/thorax-2024-221772. PMID: 39153860; PMCID: PMC11671978.

Maher TM, Brown KK, Cunningham S, DeBoer EM, Deterding R, Fiorino EK, Griese M, Schwerk N, Warburton D, Young LR, Gahlemann M, Voss F, Stock C; InPedILD trial investigators. Estimating the effect of nintedanib on forced vital capacity in children and adolescents with fibrosing interstitial lung disease using a Bayesian dynamic borrowing approach. Pediatr Pulmonol. 2024 Apr;59(4):1038-1046. doi: 10.1002/ppul.26882. Epub 2024 Jan 30. PMID: 38289091.

PubMed Link

Publications on PubMed

Research

Research Topics

Long COVID in children including etoiology, therapy and clincal trials.
Pollution impact on maternal and child health in the context of global health.
Clinical trials in childhood lung fibrosis and long COVID.
Mechanisms of organ development and disease: lung, gut, heart, etc.
Advanced imaging and 3D printing of tissue (lung) structure.

Research Focus

Dr. Warburton has been continually funded by the NIH, NSF, CMDRP, CIRM, ALA, AHA and other agencies for over 40 years. He has published over 300 papers which have been cited over 25,000 times, his H-factor is >80 and he is rated nationally as the most read researcher in this Department and above the 5% percentile for all pediatricians globally.