CeVD Study

IRB
CHLA-21-00026
Non-invasive Biometric Screening for Cerebrovascular Disease (CeVD) in Young Persons with Down Syndrome

An investigation of the utility of non-invasive transcranial Doppler (TCD) ultrasound in the prediction of moyamoya disease in persons with Down syndrome with the goal of identifying cerebrovascular disease before it causes a stroke.

Study Details
Time commitment/Requirements

Phase I: Complete a demographic and medical history intake questionnaire, obtain four blood pressure measurements, collect height and weight, and measure head and neck circumference (duration: roughly 10 minutes).

Phase II-IV: Complete a neurologic examination and neurocognitive assessment, transcranial doppler (TCD) ultrasound, MRI, and a blood draw (duration: varies).
Keywords
cerebrovascular disease down syndrome, screening, stroke, stroke prevention
Study Type
Diagnostic
Eligibility
Individuals with a diagnosis of Down syndrome are eligible to participate. Age range is 8-26 years of age.
Does this study also recruit healthy volunteers?
No
Enrollment Status
Open
Label
Research Contact
Contact Email
dsresearch@chla.usc.edu
Phone
(323) 607-3505