Extubation failure in newborn infants

IRB
CHLA-14-00451
A study of incidence of upper airway obstruction and other risk factors of extubation failure in newborn infants

Validate the use of respiratory inductance plethysmography (RIP) and esophageal manometry in diagnosing upper airway obstruction (UAO) in newborn infants.

Study Details
Keywords
upper airway obstruction extubation failure in babies, RIP, UAO, respiratory inductance, plethysmography
Study Type
Interventional
Eligibility
Intubated and mechanically ventilated infants admitted to Newborn and Infant Critical Care Unit (NICCU) at the Children’s Hospital Los Angeles. Infants needed to have been intubated for at least 12 hours, with a plan for extubation by the clinical care team. Inclusion criteria also includes recent (within 24 hours) evidence of stable chest x-ray in advance of extubation and, where applicable, documentation of either closed or non-significant PDA on the last echocardiogram.
Does this study also recruit healthy volunteers?
No
Enrollment Status
Open
Coordinator Contact
Kinnedy Houston
Contact Email
kihouston@chla.usc.edu
Coordinator Contact
Sharon Tang
Contact Email
shatang@chla.usc.edu