Content related to Combination Therapy May Offer Better Outcomes for Patients with Retinoblastoma

Microscopic image: MDM2 expression (in red) in retinoblastoma Rb176 cells. Credit: Donglai Qi, PhD, and David Cobrinik, MD, PhD. Researchers at The Saban Research Institute of Children’s Hospital Los

Researchers are working to uncover a cause for retinoblastoma, the most common eye cancer in children. They have published promising results in the journal Nature.

The Stem Cell Analytics Core facilitates stem cell research and innovation for all investigators at CHLA.

Retinoblastoma is a common eye cancer in children. David Cobrinik of The Vision Center has helped answer the question of why mutations to the RB1 gene primarily cause tumors of the retina.

In 2006, researchers studying obesity stumbled upon a gene called PID1 (Phosphotyrosine Interaction Domain containing 1). They found the gene played a role in insulin resistance in obese patients

Researchers at The Saban Research Institute, Cedars-Sinai Medical Center and Caltech have unveiled a novel nanoparticle complex that induces tumor cell death while enhancing contrast in MRI images.