Content related to A High-Tech Look at Rejection in Pediatric Liver Transplants

Researchers are searching for biomarkers to better identify which children with acute liver failure will recover on their own—and which will need a liver transplant.

In a worldwide pediatric study, researchers from Children’s Hospital Los Angeles show the clear benefit of using living donor liver tissue for transplants.

Living donation and significantly lower wait times helped the program to perform 35 liver transplants in 2022.

CHLA core facilities share a common theme: The staff pride themselves on providing leading-edge technology, but they are also truly invested in the experiments and the scientists themselves.

Michael joined the Single Cell, Sequencing, and CyTOF (SC2) Core in 2018. In his role, he assists scientists in identifying and quantifying various biomarkers in tissue and liquid biopsy samples.

More precise analysis aims to help transplanted organs last longer—with less immunosuppression.

The SC2 Core aims to promote and enable high-impact basic and translational research by establishing novel and evolving technologies and instrumentation for investigators at CHLA and USC. Led by

Rachel Lestz, MD, not one to mince words or to conserve them, is abruptly stuck in a pause, halfway between a plausible hypothetical and an oncoming dilemma. “Am I that curious a person?” she asks