Content related to New Approach to Modeling Ewing Sarcoma Leads to a Novel Discovery

A physician-scientist is harnessing the power of zebrafish—and a new, state-of-the-art facility—to develop innovative treatments for solid tumors in children.

Shedding epithelial cells in the intestine. Image courtesy of Mark R. Frey, PhD, The Saban Research Institute, Children’s Hospital Los Angeles. The lining of the intestine is the most rapidly-renewing

Research at Children’s Hospital Los Angeles enables a novel compound to achieve a key designation from the Food and Drug Administration.

Microscopic image: MDM2 expression (in red) in retinoblastoma Rb176 cells. Credit: Donglai Qi, PhD, and David Cobrinik, MD, PhD. Researchers at The Saban Research Institute of Children’s Hospital Los

Investigators at the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles have identified new findings about an immune cell – called a tumor-associated macrophage – that

Program combines clinical expertise and basic science to advance care in an understudied cancer.

In 2006, researchers studying obesity stumbled upon a gene called PID1 (Phosphotyrosine Interaction Domain containing 1). They found the gene played a role in insulin resistance in obese patients

Researchers at The Saban Research Institute, Cedars-Sinai Medical Center and Caltech have unveiled a novel nanoparticle complex that induces tumor cell death while enhancing contrast in MRI images.

Scientists at Children’s Hospital Los Angeles develop first physiologically-accurate in vitro model of the human kidney glomerulus, representing a milestone in the field of kidney disease research