Christian Hochstim, MD, PhD
Christian Hochstim completed a fellowship in pediatric otolaryngology at Stanford with broad training in a range of complex problems including airway reconstruction, aerodigestive disorders, surgical treatment of obstructive sleep apnea, and hearing loss and cochlear implantation. He also completed a PhD in developmental biology at Caltech, and his current research focuses on stem cell and regenerative medicine based approaches to laryngeal and tracheal reconstruction and prevention of stenosis.
Complex airway disorders, children with tracheostomy, stridor and noisy breathing, drooling and aspiration, subglottic and tracheal stenosis, voice disorders, vocal cord paralysis, laryngomalacia, obstructive sleep apnea, hearing loss, cholesteatoma, head and neck masses and tumors
Education
USC Keck School of Medicine
California Institute of Technology (PhD)
USC Keck School of Medicine, Otolaryngology
USC Keck School of Medicine, Otolaryngology
Stanford University, Lucile Packard Children’s Hospital, Pediatric Otolaryngology
Accomplishments
American Board of Otolaryngology
California Medical Board
American Academy of Otolaryngology-Head and Neck Surgery
American Medical Association
American Society of Pediatric Otolaryngology Meeting, First Place Poster – Basic Science, 2014
Cohen-Geller Award, Pediatric Otolaryngology, Children’s Hospital of Los Angeles, 2012
Mark S. Ehrenreich Prize - Medical Ethics, USC Keck School of Medicine, 2009
Publications
Selected Publications:
Bacterial biofilms and increased bacterial counts are associated with airway stenosis. Mazhar K, Gunawardana M, Webster P, Hochstim C, Koempel J, Kokot N, Sinha U, Rice D, Baum M. Otolaryngol Head Neck Surg. 2014 May;150(5):834-40. doi: 10.1177/0194599814522765. Epub 2014 Feb 10.
A novel orthotopic mouse model of head and neck cancer and lymph node metastasis. Masood R, Hochstim C, Cervenka B, Zu S, Baniwal SK, Patel V, Kobielak A, Sinha UK. Oncogenesis. 2013 Sep 9;2:e68. doi: 10.1038/oncsis.2013.33.
Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition. Sinha UK, Schorn VJ, Hochstim C, Chinn SB, Zhu S, Masood R. Head Neck. 2011 Feb;33(2):178-88. doi: 10.1002/hed.21418.
Biofilm detection with hematoxylin-eosin staining. Hochstim CJ, Choi JY, Lowe D, Masood R, Rice DH. Arch Otolaryngol Head Neck Surg. 2010 May;136(5):453-6. doi: 10.1001/archoto.2010.62.
Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Hochstim C, Deneen B, Lukaszewicz A, Zhou Q, Anderson DJ. Cell. 2008 May 2;133(3):510-22. doi: 10.1016/j.cell.2008.02.046.
Research
Molecular mechanisms of laryngeal and tracheal stenosis formation, laryngeal and tracheal development, stem cells and laryngeal and tracheal regeneration