The first Phase IIb clinical trial in Down syndrome regression disorder (DSRD). An open-label, randomized study comparing the safety and efficacy of lorazepam, intravenous immunoglobulin (IVIg) and the Janus Kinase inhibitor (JAK inhibitor), tofacitinib.
Validate the use of respiratory inductance plethysmography (RIP) and esophageal manometry in diagnosing upper airway obstruction (UAO) in newborn infants.
Two main purposes of the study: (1) to see if social communication of children with TSC can be improved with a short term behavioral intervention (JASPER) and (2) to see if these improvements remain long after the study, and whether they can be observed with electroencephalography (EEG).
To determine if a home visitation program for breastfeeding mothers affects the health of their babies.
