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COVID Brain Fog Study

Comparing brain MRIs, blood brain barrier integrity and cognitive performance in those with and without Long COVID symptoms and in those that have and have notbeen previously hospitalized with COVID.

CP bone

To investigate bone health in cerebral palsy and the relationship between walking and bone health.

CTC

The purpose of the study is to learn about how to improve access to care during young adulthood and to assess if telehealth is an acceptable form of care.

Diurnal Study

This study is a randomized, double-blind, active-controlled, titrated, parallel arm, multicenter study. It will compare the efficacy, safety and tolerability of twice daily Chronocort with twice daily IRHC (Cortef®) over a randomized treatment period of up to 52 weeks in participants aged 16 years and over with known classic CAH due to 21-hydroxylase deficiency. The primary efficacy assessment of biochemical responder rate and the key secondary assessments of dose responder rate and mean total daily dose will be assessed after 52 weeks of randomized treatment.

DSRD Clinical Trial

The first Phase IIb clinical trial in Down syndrome regression disorder (DSRD). An open-label, randomized study comparing the safety and efficacy of lorazepam, intravenous immunoglobulin (IVIg) and the Janus Kinase inhibitor (JAK inhibitor), tofacitinib.

Fontan Non-Newtonian Behavior

To evaluate the impact of non-Newtonian behavior on hemodynamic efficiency in children and young adults who have undergone the Fontan procedure.