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To find out safety and effectiveness of dupilumab (Dupixent) in infants with severe eczema.

To find out the effects of dupilumab (Dupixent) on skin infection in eczema.

Hydroxychloroquine is given as an investigational drug to relatives of someone with type 1 diabetes who have positive diabetes antibodies in an attempt to prevent or delay the onset of type 1 diabetes. See website for more details https://www.trialnet.org/our-research/prevention-studies/hydroxychloroquine-hcq

To demonstrate that an ultra-fast-acting formulation of insulin lispro is non-inferior to Humalog on measures of glycemic control when administered 0 to 2 minutes before eating in combination with basal insulin.

This research is being done to test the safety and effectiveness of intranasal carbetocin to treat Prader Willi Syndrome.

To collect information on the long-term effects of XLH on children and adults who have participated in burosumab clinical trials, adults and children who have not participated in burosumab clinical trials, and who may or may not have been treated with burosumab during the course of the study.

This study will evaluate the effect of Denosumab on lumbar spine mineral density (BMD), as assessed by dual-energy X-Ray absorptiometry (DEXA) at 12 months in children 5 to 17 years of age with GIOP.

To find out which of two commonly used IV fluids given in the Emergency Department for sepsis is most effective.

To find out the effects of tenofovir alafenamide (TAF) on children and adolescents with chronic hepatitis B.

To find out the effects of Maralixibat on the treatment of PFIC.