Content related to Faster Lung Function Decline in Cystic Fibrosis Linked to High Sputum Levels of Pf Bacteriophage

Children’s Hospital Los Angeles takes a team approach to cystic fibrosis care, with a focus on finding next-generation treatments.

Dr. Burgener is exploring whether a tiny virus can help guide treatment for children with cystic fibrosis who have chronic airway infections.

Children’s Hospital Los Angeles researchers find that most children with sickle cell anemia do not get basic preventive care.

Dr. Joy Gibson is researching how to optimize the use of antibiotics and other strategies to manage infections in patients with cystic fibrosis.

Sickle cell disease (SCD) is one of the most common genetic blood disorders, affecting over 100,000 Americans and 1 in 365 African-American newborn babies. It is an autosomal recessive condition

Born at 29 weeks, Sam suffered from subglottic stenosis, his airway so narrowed it was 95% closed. Doctors in CHLA’s Aerodigestive Program worked to rebuild it.

A specialized low-salt fasting-mimicking diet restores kidney function in preclinical animal models and patients with chronic kidney disease.

A CHLA clinical trial finds that N-acetylcysteine may be a promising next-generation therapy to reduce the risk of cisplatin-induced hearing loss.

Four investigators share their research—and how the USC/CHLA facility will help bring novel cell therapies to clinical trials faster.