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Content related to Long-Term Neurocognitive Effects Linked to Chemotherapy-Induced Hearing Loss

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Research and Breakthroughs

Increased Risk of Metabolic Disorders for Some Children with Spina Bifida

March 22, 2016
Representative quantified computed tomography (CT) slices showing excess adipose or fatty tissues (pink) within the muscle boundary (green) in spina bifida patients (right) compared to control
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Research and Breakthroughs

Basic Research Led to First FDA-Approved Immunotherapy for Pediatric Cancer

February 4, 2016
Neuroblastoma cells under a microscope labeled with fluorescent molecules. Image courtesy of Shutterstock. Building upon more than two decades of basic research conducted at Children’s Hospital Los
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Research and Breakthroughs

An Inside Job: Using DNA to Target Cancer

December 6, 2018
While other toddlers her age were fighting naptime, two-year-old Michelle was battling an aggressive, life-threatening cancer. Doctors at Children’s Hospital Los Angeles saved her life in an epic
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Aerial view of the CHLA Anderson Pavilion Building.
Press Release

Study Suggests Need to Include Overweight Subjects in Metabolic Research

August 23, 2018
CHLA investigators spotlight the need to include obese and overweight subjects in metabolic research to prevent potentially misleading outcomes. Children's Hospital Los Angeles investigators have
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Side-by-side comparison of damaged and undamaged lung cells
Research and Breakthroughs

Baby’s Breath: A New Way to Study Neonatal Lung Disease

February 16, 2016
Normal lung (image A) compared to lung developed with low levels of VEGF (image B) demonstrating abnormal air spaces and lung tissue. Photo courtesy of Grikscheit Lab, The Saban Research Institute of
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After-Radiation-Therapy.jpg
Press Release

PENTEC: World Experts Team Up to Improve Outcomes for Children After Radiation Therapy

May 13, 2021
More than 150 specialists worldwide provide evidence-based guidance to reduce long-term effects of radiation therapy in children.
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Research and Breakthroughs

Oncoproteins Interact to Promote Cancer Cell Growth in Retinoblastoma

October 17, 2016
Microscopic image: MDM2 expression (in red) in retinoblastoma Rb176 cells. Credit: Donglai Qi, PhD, and David Cobrinik, MD, PhD. Researchers at The Saban Research Institute of Children’s Hospital Los
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Woman wearing a blue medical procedure, holding a young girl, who is also wearing a medical procedure mask, while talking to a doctor.
Research and Breakthroughs

$1.92 Million Grant Funds Research into Pain Management Techniques for Kids

August 22, 2022
Could mind-body pain management techniques replace medication for kids with chronic conditions?
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A male and female doctor stand pose by side wearing white lab coats and blue medical procedure masks.
Care Innovation

Advancing Care and Innovation for Pediatric Brain Tumors

January 27, 2023
The Brain Tumor Center at Children’s Hospital Los Angeles takes a team approach—and offers one of the largest clinical trial programs of its kind.
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