New Research From the Neurological Institute Team
Do patients with pediatric-onset multiple sclerosis relapse more frequently if their initial treatment is delayed? If endoscopic third ventriculostomy fails in hydrocephalus, how does it affect later shunt placement? And can a combination of electroencephalography (EEG) markers provide a clearer picture of autism-related circuitry?
These are just some of the research questions addressed in recently published studies from faculty at the Neurological Institute at Children’s Hospital Los Angeles. Below are links to several papers team members have published over the past few months.
Pediatric-onset multiple sclerosis
Delayed initiation of disease modifying therapy increases relapse frequency and motor disability in pediatric onset multiple sclerosis
(Saba Jafarpour, Soniya Pinto, My H Vu, Mellad M Khoshnood, Nusrat Ahsan, Laura E Saucier, Jonathan D Santoro)
Multiple Sclerosis and Related Disorders
July 2024
Sexual health education and quality of counseling in pediatric-onset multiple sclerosis
(Kelly Burk, Dania Pagarkar, Mellad M Khoshnood, Saba Jafarpour, Nusrat Ahsan, Wendy G Mitchell, Jonathan D Santoro)
Pediatric Neurology
August 2024
Down syndrome regression disorder
De novo variants in immune regulatory genes in Down syndrome regression disorder
(Saba Jafarpour, Abhik K Banerjee, Mellad M Khoshnood, Benjamin N Vogel, Natalie K Boyd, Lina Nguyen, Rebecca Partridge, Stephanie L Santoro, Grace Y Gombolay, Kristen S Fisher, Diego Real de Asua, Maria Carmen Del Ortega, Cathy Franklin, Michael S Rafii, Jonathan D Santoro)
Journal of Neurology
August 2024
Hydrocephalus
Ventriculoperitoneal shunt placement following endoscopic third ventriculostomy failure in the treatment of pediatric hydrocephalus
(Alexander R Evans, Lance Villeneuve, Ira Bowen, Lacey Carter, Sixia Chen, Marianne Kimmell, Joanna Gernsback, Karl Balsara, Andrew Jea, Virendra R Desai)
Journal of Neurosurgery Pediatrics
August 2024
Anti-CD20 therapy in children with severe Epstein-Barr virus-associated meningoencephalitis
(Sana Ahsan, Saba Jafarpour, Mellad M Khoshnood, Deepti Nagesh, Eugenia Ho, Nusrat Ahsan, Jonathan D Santoro)
Journal of Child Neurology
Sept. 5, 2024 (online)
Autism spectrum disorder
Parsing evoked and induced gamma response differences in Autism: A visual evoked potential study
(Abigail Dickinson, Declan Ryan, Gabrielle McNaughton, April Levin, Adam Naples, Heather Borland, Raphael Bernier, Katarzyna Chawarska, Geraldine Dawson, James Dziura, Susan Faja, Natalia Kleinhans, Catherine Sugar, Damla Senturk, Frederick Shic, Sara Jane Webb, James C McPartland, Shafali Jeste; Autism Biomarkers Consortium for Clinical Trials)
Clinical Neurophysiology
September 2024
Multi-site EEG studies in early infancy: Methods to enhance data quality
(Abigail Dickinson, Madison Booth, Manjari Daniel, Alana Campbell, Neely Miller, Bonnie Lau, John Zempel, Sara Jane Webb, Jed Elison, Adrian K C Lee, Annette Estes, Stephen Dager, Heather Hazlett, Jason Wolff, Robert Schultz, Natasha Marrus, Alan Evans, Joseph Piven, John R Pruett Jr, Shafali Jeste; IBIS Network)
Developmental Cognitive Neuroscience
October 2024
Radiology findings
When is the radiology report of posterior fossa containing cyst/cystic-like CSF collection of clinical or surgical significance?
(Jeffrey J Quezada, Marvin D Nelson, J Gordon McComb)
Journal of Neurosurgery Pediatrics
October 2024
